FACTORS GOVERNING THE EXCRETION RATE OF UREA

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The Numerical Laws Governing the Rate of Excretion of Urea and Chlorides in Man

1. The excretion of urea and of chlorides in the normal individual is carried out according to definite laws, capable of numerical expression. 2. The rate of excretion of urea and of sodium chloride is determined by the concentration in the blood, the rate of water output, and indirectly by the weight of the individual. 3. The threshold of sodium chloride excretion is practically constant at ab...

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The Rate of Urea Excretion. Vii. the Effect of Various Other Factors than Blood Urea Concentration on the Rate of Urea Excretion.* by T. Addis

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The Rate of Urea Excretion. Iii. the Effect of Changes in Blood Urea Concentration on the Rate of Urea Excretion. by T. Addis and C. K. Watanabe

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The Rate of Urea Excretion. Iv. the Effect of Changes in the Volume of Urine on the Rate of Urea Excretion

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Mechanism of Urea Excretion

1. Urea is present in the cells of the proximal convoluted tubule in a concentration higher than that of the blood or than that of the cells of any of the other kidney tubules. 2. Such a condition can only be reconciled to an assumption of an active secretion (excretion) on the part of these cells. 3. Urea also passes through the glomerular filter with the other crystalloids of the blood plasma...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1921

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)86162-2